he prognosis of triple negative breast cancer (TNBC) is closely associated with the tumor microenvironment (TME). TME drives TNBC invasion and metastasis through mechanisms such as vascular abnormalities, stromal stiffening, and immune suppression, which are critical factors contributing to treatment failure in TNBC. Therefore, a deeper understanding of TME is of great significance for improving therapeutic efficacy and survival outcomes in TNBC. With advancements in science and technology, multimodal ultrasound has emerged as efficient tools for non-invasive and dynamic visualization of TME. This article reviews the characteristics of TNBC TME and the progress in the application of multimodal ultrasound imaging and artificial intelligence for TME visualization, aiming to provide guidance for the precise diagnosis, treatment, and personalized management of TNBC