Abstract:Hypertriglyceridemia (HTG) is a well established but often missdiagnosed cause of acute pancreatitis. The mechanism responsible for HTG-AP is related to free fatty acid (FFA) lipotoxicity, microcirculatory disorder, oxidative stress, Ca2+ overload, and genetic polymorphism. HTG-AP is often associated with greater clinical severity and rate of complications. Therefore, accurate diagnosis of HTG-AP as soon as possible is essential so that patients receive the appropriate treatment. In 2021, based on consensus development conference, experts on emergency medicine from all over the country had built consensus on definition, etiology, pathogenesis, clinical features, severity classification, etiology treatment, routine treatment and other aspects of HTG-AP, and formed the highly operable “Emergency Management of Hypertriglyceridemia Acute Pancreatitis: a consensus statement”. The content of this consensus was not only accords with the important international guidelines and consensus, but also had distinct characteristics of hyperlipidemia concept, methods and strategies. It was the first global expert consensus on the diagnosis and treatment of hypertriglyceridemia pancreatitis. The consensus has been released for one year, which has played a positive role in promoting the accurate and efficient diagnosis and management of HTG-AP in China. However, clinicians, especially emergency physicians, still have many questions about how to control serum TG level and prevent the occurrence of systemic inflammatory response syndrome in emergency department. This present review aims to interpret the reported 15 recommendation of this consensus by reviewing the recent literature on the topic of HTG-AP.