Stroke is the first cause of death in our country. The main pathogenesis of cerebral infarction is blood flow restriction caused by vascular occlusion or vascular embolism, resulting in cerebral ischemia and hypoxia. According to different sources of emboli, some scholars have proposed the TOAST etiological classification. At present, for the treatment of different etiological types of ischemic stroke in the acute phase, especially the cardioembolic type, domestic and foreign guidelines and expert consensus have been partially updated. The etiology classification of acute ischemic stroke is the main line, and the updated AIS guidelines and expert consensuses at home and abroad in recent years are interpreted in order to provide a reference for the selection of clinical diagnosis and treatment plans and achieve individualized optimal treatment.