Pestle and needle therapy, namely "Li Zhongyu pestle and needle therapy", is a national intangible cultural heritage and the treasure of Sichuan medicine. It has the effects of acupuncture and massage. At present, it is widely used in clinic and has a good therapeutic effect. There is no unified specification for pestle and needle operation, and there is no clear basis or principle for its operation process. Based on the rules of evidence-based medicine, this paper consulted the relevant literature at home and abroad on the basic operation methods, operation time and frequency, disinfection and curative effect evaluation of pestle needle, demonstrated the content through two rounds of Delphi expert consultation and expert meeting, and formed the pestle needle operation specification and quality evaluation standard. It includes two aspects: pestle needle operation specification and quality evaluation standard. The pestle needle operation specification is carried out from the basic technique, angle, time and frequency; The quality evaluation standard involves 10 first-class indicators, 24 second-class indicators and 25 third-class indicators such as instrument, check, evaluation, notification, material preparation, environment and patient preparation, operation process, post operation disposal, evaluation and theoretical questions. It has a certain scientific nature, standardizes the clinical operation of pestle and needle, provides guidance for clinical practice, and thus ensures the clinical safety and efficacy of patient treatment.