【摘要】 目的 调查民众对新型冠状病毒肺炎（COVID-19）期间居家隔离防护的认知、态度和行为情况，为针对性强化疫情防控提供科学数据依据。 方法 采用滚雪球抽样方法从2020年2月16日～2月20日，使用问卷星编制调查表，通过网络对全国29个省、市、自治区的民众就COVID-19和居家隔离的相关知识、居家隔离防护态度、行为及心理状态进行调查。〖HTH〗结果 调查回复1121人纳入研究对象。新冠肺炎的相关知识得分平均（60.59±17.79）分，不同年龄、性别、文化程度、职业的人群得分差异有统计学意义（P均＜0.05）。有82.07%的民众了解居家隔离防护的相关知识，获得途径主要为微信（78.59%）、电视（58.07%）和网页（48.8%）。72.70%的民众希望医务工作者为其提供照护指导，形式主要为微信（73.86%）和电话指导（61.73%）。1121人心理量表得分平均（15.63±5.53）分，心理状态维持较好的有969例（86.4%），不同文化程度的人群差异具有统计学意义（P＜0.05）。 结论 新冠肺炎疫情出现后，通过政府和社会对居家隔离防护的宣传和指导，绝大多数民众对疫情能高度关注，疾病和防护的认知度高，态度端正，对采取的防护措施能积极配合，且心理状态维持较好；但仍有少数民众还需要加强宣传教育和实施差异化、个体化指导，不留死角，促进抗击新冠肺炎的全面胜利。
【Abstract】 Objective To analysis the cognition, attitude and behavior of home segregation and protection during the breakout of Coronavirus disease (COVID-19) in China. Methods Subjects from 29 provinces were invited to participate in a questionnaire online survey (https://www.wjx.cn/) from Feb 16Feb20,2020. Results A total of 1121 subjects were included in our study. The score of knowledge about COVID19 was （60.59±17.79). There was a significant difference in scores among different age, gender, education level and occupation (P＜0.05). 82.07% of the residents knew the knowledge of home isolation and protection, and the main access was WeChat (78.59%), TV (58.07%) and website (48.8%). 72.7% of the residents hope that the medical workers to provide care guidance, mainly in the form of WeChat (73.86%) and telephone (61.73%). The average score of K10 was (1563±553). There were 969 cases (86.4%) with good psychological state. The difference of different education level was statistically significant (P＜0.05). Conclusion After the outbreak of COVID-19, through the propaganda and guidance of the government and society for home quarantine, most people pay close attention to the epidemic situation, have high awareness of disease. They have a positive attitude, cooperate well with the protective measures taken by the government. Meanwhile, the residents maintain a good psychological state, but there are still a few them who have different problems. The government needs to strengthen publicity and education, and implement individualized guidance, the COVID19 could be promoted without leaving dead ends.