【Abstract】 Objective To investigate the application advantages of the visual lateral approach transversus abdominis plane (TAP) block anesthesia under ultrasonographic visualization infor peritoneal dialysisthe application of PD catheter insertion.Methods〓We analyzed 40 patients from the third people's Hospital of Chengdu with endstage renal disease underwent PD catheter insertion between August 2016 to August 2017. The patients were randomly divided into TAP block group and local anesthesia group 20 cases in each group. The score of visual analogue scale（VAS）were record during and after the surgery. We recorded operation time, the dosage of additional anesthesia drug, and the number of patients used postoperative analgesic, doctors and patients satisfaction, and the occurrence of adverse reaction, and outcome cases.Results Each of 20 patients were included in the local anesthesia group while the other 20 cases inand the TAP block group. The VAS scores during and after the surgery in the TAP block group were lower than those in the local anesthesia group. There were significant differences (P＜005). The TAP block group was used less consumption of ropivacaine during the operation than the local anesthesia group (38±1174ml vs 54±926ml, t=478, P＜005). The anesthetic satisfaction of the surgeon and the postoperative patient's satisfaction and was significantly higher in the TAP block group than in than the local anesthesia group in the anesthetic satisfaction of the surgeon and the postoperative patient's satisfaction(χ2=491; χ2=812，P＜005 ). There was no significant difference between the two groups in the adverse reaction of anaesthesia (P＞005). The outcome offor followup of the TAP block group is superior to the local anesthesia group(χ2=2042, P＜005).Conclusion The visual lateral approach TAP block for peritoneal dialysis catheter is a minimally invasive, safe, and effective anesthesia.