【Abstract】Hypertrophic Cardiomyopathy (HCM) is a primary cardiomyopathy with a genetic tendency and characterized by myocardial hypertrophy. HCM also has been the leading cause of the sudden death of adolescent and athletes. It may occur at any age and race. Heterogeneity exists in clinical manifestations, types of genic mutations and the rate of progression of HCM. Hence, it is of vital importance to early diagnose the disease and evaluate its severity and prognosis. Cardiac Magnetic Resonance (CMR) as for an important examination method has significant implications for the evaluation of cardiac structure, function, myocardial viability and molecular imaging. This study aims to review the clinical value of CMR multimodality imaging in the establishment of diagnosis and treatment of HCM and the progress of research in recent years.