【Abstract】 Rheumatoid arthritis is an autoimmune joint disease. Its pathogenesis may be related to environmental, genetic and immune factors. At present, RA currently mainly relies on clinical symptoms, experimental examination and imaging examination for diagnosis, among which experimental examination is mainly based on autoantibody examination. In recent years, with the deepening of relevant researches, many achievements have been made in the research on autoantibodies of RA at home and abroad. This paper reviews the recent advances in the study of autoantibodies in RA.