Abstract:【Abstract】Objective To investigate the effects of hemorheology and coagulation parameters on perinatal outcomes in patients with hypertensive disorder complicating pregnancy. Methods 136 patients with hypertensive disorder complicating pregnancy in our hospital from February 2017 to January 2019 were selected as subjects. Another 136 normal pregnant women admitted to the hospital were selected as the control group. The changes of blood rheology and coagulation function indexes in the third trimester were compared between the two groups. The complications and perinatal outcomes of patients with abnormal hypercoagulability index in patients with hypertensive disorder complicating pregnancy were observed.Results Compared with the normal pregnancy group, PT, aPTT, and TT in the third trimester of pregnancy were significantly lower (P<005), and Fbg was significantly increased (P<005). Whole blood high and low cut viscosity, plasma viscosity, high and low cut reduction viscosity Hematocrit, erythrocyte deformation index, erythrocyte electrophoresis time, and fibrinogen were significantly increased (P<005). In patients with hypertensive disorder complicating pregnancy, the abnormal renal function, abnormal liver function and retinopathy of patients with abnormal coagulation function index ≥3 were significantly higher than those with abnormal blood coagulation index 1~2 (P<005). The neonatal weight, the 1minute Apgar score of patients with abnormal coagulation function index ≥ 3 were significantly lower than those with abnormal blood coagulation index 1~2 (P<005). The incidence of perinatal death, cesarean section of patients with abnormal coagulation function index ≥3 were significantly higher than those with abnormal blood coagulation index 1~2 (P<005).Conclusion The blood rheology and coagulation function indexes of patients with hypertensive disorder complicating pregnancy were significantly abnormal, and the complications of gestational hypertension and the occurrence of adverse perinatal outcome were significantly correlated with the abnormal degree of coagulation function.