高原地区妊娠高血压胎儿左室缩舒功能的组织多普勒成像评价
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青海省卫生和计划生育委员会科研项目


Tissue doppler imaging evaluation of left ventricular systolic function in pregnancyinduced hypertensive fetus in highland
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    摘要:

    【摘要】 目的 探讨组织多普勒成像(TDI)对高原地区妊娠高血压胎儿左室缩舒功能的应用价值。方法 选取2016年05月~2017年12月青海大学附属医院收治的64例高原地区妊娠高血压孕妇作为观察组,选取同期正常妊娠妇女64例作为对照组,均对胎儿行心脏彩色多普勒检查,评估胎儿的左室形态、收缩和舒张功能情况,其中TDI指标包括舒张早期E波峰值速度(Em)、舒张晚期A波峰值速度(Am)、收缩期S波峰值速度(Sm)、计算Em/Am比值。结果 随着胎儿胎龄增长,两组胎儿左室厚度均增高,但观察组胎儿左室间隔和侧壁、前壁和下壁厚度均明显比对照组高(P<0.05);随着胎儿胎龄的增长,两组胎儿左室间隔和侧壁、前壁和下壁Em、Am及Sm均增高,Em/Am增大(P<0.05),且不同时期观察组胎儿左室4个室壁的Em、Em/Am、Sm均明显比对照组低(P<0.05),但Am比对照组明显高(P<0.05)。结论 高原地区妊娠高血压胎儿左室舒张功能与收缩功能受损,TDI可敏感有效反应其心脏功能变化,具有重要的临床价值。

    Abstract:

    【Abstract】 Objective To investigate the value of Tissue Doppler Imaging (TDI) on left ventricular systolic function in pregnancyinduced hypertensive fetus in highland. Methods 66 pregnant women with hypertension in our hospital from May 2016 to December 2017 were selected as the observation group. 64 normal pregnant women in the same period were selected as the control group. All fetuses underwent cardiac color Doppler examinations to assess fetal left ventricular morphology, systolic and diastolic function. Among them, the TDI indexes included: diastolic early E wave peak (Em), late diastolic A (Am), systolic Swave peak velocity (Sm), calculated Em / Am ratio. Results With the increase of fetal gestational age, left ventricular thickness increased in both groups. However, the thickness of left ventricular septum, lateral wall, anterior wall and inferior wall in the observation group were significantly higher than those in the control group (P<0.05).; With the increase of fetal gestational age, Em, Am of the left ventricular septum, lateral wall, anterior and inferior wall increased, Sm and Em/Am of the two groups increased (P<0.05). The Em of the left ventricular wall in the observation group was significantly lower than that of the control group in different periods. The Em / Am was lower than the control group. The Am was significantly higher than the control group. The Sm were significantly lower than the control group (P<0.05). Conclusion Left ventricular diastolic function and contractile function are impaired in fetus with gestational hypertension in high altitude area. TDI can diagnose changes of cardiac function sensitively and effectively, and it has important clinical value.

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  • 在线发布日期: 2019-09-10
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