Objective To investigate the value of twodimensional speckle tracking echocardiography (STE)in evaluating left ventricular myocardial motor function of Kawasaki disease (KD) children at different phases. Methods 47 KD children treated in the pediatrics department of our hospital from January 2017 to December 2017 were selected and divided into acutephase group (n=11), convalescent phase group (n=12) and chronic phase group (n=24). 55 healthy children were set as control group. The left ventricular myocardial motor function of 102 children was assessed by STE. Results The GLS, GCS and GCSR were lowest in control group (P＜0.05). The GLS was lower in the acute phase group and chronic phase group than in the control group (P＜0.05). The decreasing degree of GCSR in the convalescent phase group was more significant than in the chronic phase group (P＜0.05). The LVRWT of the acute phase group was higher than that of the convalescent phase group and chronic phase group (P＜0.05). The lateral wall myocardial early diastolic velocity was higher in the convalescent phase group than in the acute phase group and chronic phase group (P＜0.05), as well as higher in the control group than in the acute phase group (P＜0.05). Conclusion Different degrees of left ventricular myocardial motor function deformation are existed in KD children, so the twodimensional STE dose have certain evaluative value for the KD children.