外周血中可溶性白细胞分化抗原14与胎膜早破及围产儿感染的关系
DOI:
作者:
作者单位:

作者简介:

通讯作者:

基金项目:


The effect of sCD14 on premature rupture of membrane and perinatal infection in peripheral blood
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    【摘要】目的 探讨外周血中可溶性白细胞分化抗原14(sCD14)与胎膜早破及围产儿感染的关系。方法 选取2015年4月~2016年12月重庆市南岸区人民医院收治的胎膜早破初产妇50例为研究组,选取同期住院的正常妊娠妇女50例为对照组。入组对象入院后取母静脉血,胎儿娩出后取脐静脉血,围产儿产出后取围产儿静脉血,Elisa 法检测各组母静脉血、脐静脉血、围产儿静脉血中sCD14水平。分别对两组母外周血、脐带血、围产儿外周血中sCD14水平进行相关性分析。将研究组按照不同破膜时间及围产儿感染情况进行分组,比较各亚组间母外周血、脐带血、围产儿外周血中sCD14水平。结果 研究组母外周血、脐带血、围产儿外周血中sCD14水平均明显高于对照组(P<0.01);研究组母外周血、脐带血、围产儿外周血中sCD14水平均呈显著正相关(P<0.05);破膜时间越久的产妇,外周血、脐带血、围产儿外周血中sCD14水平越高,组间比较差异有统计学意义(P<0.01);围产儿感染组的母外周血、脐带血、围产儿外周血中的sCD14水平均明显高于围产儿非感染组(P<0.01)。结论 sCD14与胎膜早破及围产儿感染的发生发展有一定关系,对其临床诊断具有一定的指导价值。

    Abstract:

    【Abstract】 Objective To explore the effect of sCD14 on premature rupture of membrane(PROM) and perinatal infection in peripheral blood. Methods From April 2015 to December 2016, 50 cases of PROM primiparas were selected as research group, 50 cases of normal primiparas were selected as control group. Elisa method was used to detect the sCD14 level in the blood of the mother, the umbilicus, and the perinatal infant. According to the time of PROM and the infection of the perinatal infants to group, the sCD14 levels in mother, umbilicus and peripheral infant were observed. Results The level of sCD14 in mother, umbilicus and peripheral infant of the research group were significantly higher than that in the control group (P<0.01). In research group, the level of sCD14 in mother, umbilicus and peripheral infant were positively correlated. The longer the PROM time, the higher the sCD14 level (P<0.01). The levels of sCD14 in mother, umbilicus and peripheral infant were significantly higher in peripheral infant infection group than the noninfected group (P<0.01). Conclusion The level of sCD14 is related to the development of PROM and perinatal infant infection, which has certain guiding value for clinical diagnosis.

    参考文献
    相似文献
    引证文献
引用本文
分享
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2019-05-23
您是第位访问者
版权所有:《西部医学》编辑部     蜀ICP备18038379号-4
地址:四川省成都市武侯区小天竺街75号财富国际18F-1号    邮政编码:610041
电话:028-85570072/85588403    E-mail:xbyxqk@163.com
技术支持:北京勤云科技发展有限公司