【Abstract】 Objective To investigate the value of measuring CT examination in the differential diagnosis of primary adrenal tumors. Methods The related data of patients with adrenal tumors confirmed by operation and pathology in Chongqing State District People's Hospital between January 2010 and June 2016 were analyzed. The CT findings were compared between different tumor types, and the plain scan was measured. In the second phase, CT value of scan was enhanced. Results All the 60 cases of primary adrenal tumors were unilateral lesions, and the calcification rate of cortical adenoma was 1250%, while that of pheochromocytoma was 3158% (P＞0.05); The ratios of cortical adenomas with clear boundaries, regular shape and homogeneous density were significantly higher than those of pheochromocytomas (P＜0.05); Enhanced scan of cortical adenomas showed mild to moderate homogeneous enhancement, while pheochromocytoma level cortical adenomas showed inhomogeneous enhancement. Ganglioneuroma showed slight inhomogeneous enhancement in 2 cases, and no enhancement in 4 cases; The sizes of cortical adenoma and pheochromocytoma were 100 ~ 1071cm and 331 ~ 1965cm respectively; The average CT values of plain scan, arterial phase and venous phase of cortical adenoma were significantly lower than those of pheochromocytoma(P＜0.05). Conclusion CT findings of different types of adrenal tumors are different, showing different CT values due to various tissue components. The density and enhancement degree of masses can be used for the diagnosis and differential diagnosis of primary adrenal tumors.