Abstract:【Abstract】 Objective To explore the effects of Billroth I, Billroth II and RouxenY anastomosis on perioperative indexes, gastrointestinal function recovery and complications at 1 year after operation in patients with distal radical gastrectomy. Methods 80 patients with distal radical gastrectomy from February 2015 to February 2018 in Mianyang Central Hospital were divided into group A (n=22, Billroth I anastomosis), group B (n=30, Billroth II anastomosis) AND group C (n=28, RouxenY anastomosis). The perioperative indexes and gastrointestinal recovery were recorded and compared between the two groups. After 1 years of followup, Chewwun Wu special symptom scale was used to evaluate the nutritional status of patients at 6 months after operation, and the incidence rate of complications at 1 years after operation was compared between the two groups. Results The operation time and bleeding volume of the 3 groups were C group>B group>A group (P<005). There was no significant difference in postoperative exhaust time, postoperative extubation time, oral intake time and hospital stay between A group and B group (P>005). The postoperative exhaust time, postoperative extubation time and oral intake time in C group were all later than those in A groups and B groups. The hospital stay was longer than those in A group and B group (P<005). The backflow heartburn symptom score in C group were significantly higher than those in A group and B group (P<005). The incidence rate of complications such as anastomosis inflammation, anastomotic ulcer, residual gastritis, bile reflux, reflux esophagitis and dumping syndrome was significantly higher in B group (P<005). The incidence rates of complications of anastomotic inflammation, anastomotic ulcer, residual gastritis, bile reflux, reflux esophagitis and dumping syndrome in group B were significantly higher than those in A group (P<005). Conclusion Billroth I anastomosis after distal radical gastrectomy has simple operations, good recovery of postoperative gastrointestinal function and few complications, and it is more in line with normal human physiological pathways. Billroth II anastomosis has simpler operations but more complications compared with RouxenY anastomosis. RouxenY anastomosis has complicated operations and slow recovery of postoperative gastrointestinal function, but it has good antireflux effects and safety, and few complications.