Abstract:【Abstract】 Chronic obstructive pulmonary disease (COPD),one of the most common and important chronic respiratory disease, is a great threat for public health in China. The prevalence of COPD increases exponentially in advancing age. COPD is also an agerelated disease. Frailty and sarcopenia are clinically important geriatric syndromes in geriatric medicine. The two syndromes are closely related to poor outcomes in patients with COPD. This editorial is on clinical assessment tools of frailty and sarcopenia, epidemiological evidence and biological mechanism of the two syndromes in COPD and potential intervention strategies.