【Abstract】 Objective To study the related risk factors of adverse pregnancy outcomes in patients with gestational diabetes mellitus (GDM) and hypertension. Methods 80 patients with GDM and hypertension treated in our hospital during the period from February 2014 to February 2017 were selected as the subjects. The pregnancy outcomes were recorded. The patients were divided into adverse pregnancy outcome group and nonadverse pregnancy outcome group according to the occurrence of adverse pregnancy outcomes. The clinical data such as age, prepregnancy body mass index (BMI), weight gain during pregnancy, gestational weeks of confirmed diagnosis, oral glucose tolerance test (OGTT), grade of GDM, education level, economic status, history of pregnancy, family history of diabetes mellitus, family history of hypertension and history of adverse pregnancy. Results In 80 patients with GDM and hypertension, there were 30 patients with adverse pregnancy outcomes, accounting for 375%, including 3 cases of polyhydramnios, 7 cases of premature rupture of membranes, 10 cases of premature delivery, 6 cases of postpartum hemorrhage, 8 cases of macrosomia, 5 cases of low birth weight infants, 3 cases of neonatal asphyxia and 3 cases of low birth blood glucose. The proportions of patients who were or older than 35 years old, patients whose prepregnancy BMI was or larger than 25kg/m2, patients with excessive weight gain during pregnancy, patients with 3 abnormal indexes of OGTT and patients with severe GDM in the adverse pregnancy outcome group were significantly higher than those in the nonadverse pregnancy outcome group (P＜ 005). There was no significant differences between the two groups in gestational weeks of confirmed diagnosis, education level, economic status, history of pregnancy, family history of diabetes mellitus, family history of hypertension and history of adverse pregnancy (P＞ 005). Conclusion Age, prepregnancy BMI, total weight gain during pregnancy, OGTT and grade of GDM have obvious effect on adverse pregnancy outcomes in patients with GDM and hypertension.