Abstract:Objective To investigate effect of fast track surgery on clinical symptoms and immune function in patients with colon cancer surgery. Methods The clinical data of colorectal cancer patients in general surgery department of Sichuan Zigong Fourth People's Hospital and department of general surgery of Nanchong Central Hospital were retrospectively analyzed. According to the different surgical treatment, the patients were divided into control group and observation group. The patients in the control group received routine treatment, and the patients in the observation group received the fast track treatment. The clinical symptoms, inflammation index, immunoglobulin level and cellular immune function were compared between the two groups before and after surgery. Results The incidence of thirst, hunger and hospitalization time, the first exhaust time, the first defecation time and the first time to accept semi liquid time in the observation group were better than those in the control group, the difference was statistically significant (P<0.05). The operation time of the two groups was not statistically significant (P>0.05). The CRP and IL6 in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in IgA, IgM and IgG between the two groups at T0 P>0.05). At T1 and T2, the level of IgA, IgM and IgG in the observation group was significantly lower than that of the control group, and the difference was statistically significant (P<0.05). The levels of CD3, CD4, CD8 and CD4 / CD8 at T0 were not significantly different between the two groups (P>0.05). The levels of CD3, CD4, CD8 and CD4 / CD8 at T1 and T2 in the observation group were better than those in the control group Significance (P<0.05). Conclusion The value of fast track surgery can significantly optimize the postoperative clinical symptoms and improve the cellular immune function of patients with colon cancer, and worth recommending for application.