Objective To investigate the influence of telemedicine on basal insulin treatment compliance and fasting blood glucose (FPG) in type 2 diabetes mellitus. Methods On the first day of education and baseline data acquisition of the group of 437 patients with type 2 diabetes in the subsequent 12 week follow-up by telephone and FPG of insulin dose data, combined with the "patient education" for remote health education and blood glucose control guidance for patients in a timely manner. Results The overall FPG compliance rate was 71.2% (282/396) at the 12 week follow-up period. Patients who did not participate in "special education" (x2=80.809,P＜0.001) and doctor hotline (x2=39.846, P＜0.001) had a significantly lower percentage of full submission of FPG data than the full submission of the FPG data set. The rate of insulin discontinuation for incomplete submission of FPG data was significantly higher than that for the complete submission of the FPG data group (x2=566,P＜0.001).Not attending the "doctors’hotline"(OR=0.310,95%CI:0.163-0.589)and"patient education"(OR=0.173,95%CI: 0.107-0.280) reduced treatment compliance. Not participating in "special education" will reduce the FPG compliance rate (OR=0.412, 95%CI:0.232-0.731). The results of multivariate logistic regression analysis showed that the “patient education” and “doctors’ hotline” were the important factors that influence the compliance and FPG compliance after adjustment of other influencing factors. Conclusion Telemedicine can prolong patient education and improve the compliance of patients with insulin treatment, so as to promote FPG compliance.