Objective to explore the characteristic of male androgenetic alopecia. Methods The clinical data of 363 men with AGA and 30 men with cicatricial alopecia were anlyzed。Results The onset of AGA was closely was related with both the paternal family history and matrilineal family history. The constituent ratio of subjects with family history in case group (81,26%) was higher than in control group (20%) (P＜0.05). The same trends were replicated by independent paternal/ maternal family history datasets. The constituent ratio of subjects with paternal/maternal family history in case group were 64.74% and 30.03% higher than 1334% and 6.67% in control,respectively. Man with AGA mainly inherited from his father. (P＜0.05). In this study, the average age of the men with AGA with family history was 25 years old, and the control was 27 years old. There is no statistical difference between the groups, which indicated that patients with family history may have earlier onset than those with no family history.Conclusion The results indicated that the onset of AGA was closely related with the both paternal family history and matrilineal family history. AGA is more likely to occur in the man with paternal family history than matrilineal family history. The age of onset of AGA with family history would probably be earlier than it with no family history.