青年单纯收缩期高血压研究进展
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四川省科技支撑计划项目(2012SZ0131)


Progression of isolated systolic hypertension in young individuals
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    【摘要】 单纯收缩期高血压(ISH)是老年人高血压最常见的形式,其对不良结局的预测价值也是众所周知的。然而ISH在青年人,特别是男性中也很常见,但这种情况下的预后意义仍存在争议。青年ISH是否是“假性高血压”仍不明确,最近的研究表明,青年人ISH是一种异质性状态,一些人表现为心搏量增加,另一些人表现为大动脉僵硬,或二者皆有。虽然ISH似乎是青年人群的良性疾病,但目前对其与不良结局关系的研究较少,而中国更缺少关于青年ISH的研究,未来需要长期的随访研究来更好了解青年ISH的临床意义。本文就其流行病学、发生机制及治疗等进行综述。

    Abstract:

    【Abstract】 Isolated systolic hypertension (ISH) is the most common form of hypertension in older people and its predictive value for adverse outcome is well known.However, ISH can be frequently found in young individuals, especially among males, but its prognosis is still controversial.Whether ISH in young adults represents “pseudo” or “spurious” hypertension is still unclear. Recent research has shown that ISH in young adults is a state of heterogeneity; some individuals appear to have increased stroke volume, whereas others have stiffened aortae, or both. Although ISH seems to be a benign condition in young men, Data are sparse regarding the clinical consequences of ISH in young adults, and China is less concerned with the young ISH.Future longterm followup studies are needed to better understand the clinical significance of this condition. This review provides an overview of the current understanding of ISH in young adults, including the prevalence, pathogenesis and treatment.

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  • 在线发布日期: 2018-04-18
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