【Abstract】Objective To investigate potential prediction factors of different types of lupus nephritis. Methods Clinical data of patients diagnosed as lupus nephritis (LN) by renal pathology between January 1, 2006 to January 1, 2017 were collected from our renal pathology database. Each variable was compared among different types of LN. Correlation was calculated between types of LN and each variable. Logistic multi regression analysis was used to identify significant risk factors.Results 243 patients were enrolled, including 206 females (848%). Gender, clinical manifestation and family history had no difference among subtypes. 24hour urinary protein, blood pressure and albumin were different among types.LN had highest serum creatinine level .Correlation analysis indicated increased urinary protein and anemia were correlated with type IV, increased blood pressure was correlated with type V, increased creatinine was correlated with cresentic LN and type IV. Increased urinary protein and hypoalbuminemia were independent risk factors of type IV+V and III+V. Conclusion Increased urinary protein, hypertension, anemia and increased creatinine are related to type IV, V, IV and cresentic LN, respectively. Increased urinary protein and hypoalbuminemia are independent risk factors of type IV+V and III+V. Focusing on these variables is helpful for predicting subtypes of lupus nephritis