Abstract:【Abstract】Objective To study curative efficacy of Qianlie Shutong Capsules combined with finasteride in treatment of benign prostatic hyperplasia.Methods 90 patients of benign prostatic hyperplasia received therapy from April 2015 to April 2016 in our hospital were selected as research objects. According to the draw method, the patients were divided into control group and experimental group. Two groups of patients were given routine examination, infection control, active treatment of primary diseases and other treatment. The control group was on this basis, treated with finasteride, 5mg per day, 1 time a day. The experimental group was based on the control group, treated with Qianlie Shutong Capsules, take 3 pills each time, 3 times a day. The two groups were treated for 2 months. The prostate volume, residual urine volume, maximum urinary flow rate, IPSS and NIHCPSI scores, TNF, IL17 and IL10 levels were evaluated of two groups were compared.Results The total effective rate of the experimental group was significantly higher than that of the control group[9333%(42/45)vs7333%(33/45)](P<005). The volume and residual urine volume of prostate of the experimental group were significantly lower than the control group[(2736±803)cm3 vs(3248±931)cm3, (2037±671)mL vs(2643±804)mL](P<005). The maximum urinary flow rate of the experimental group was significantly higher than that of the control group[(1709±327)mL·s1 vs(1462±306)mL·s1](P<005). IPSS and NIHCPSI were of the experimental group were significantly lower than that of the control group(P<005). TNFα and IL17 of the experimental group were significantly lower than that of the control group[(2319±838)μg/L vs(3049±1052)μg/L, (1037±236)μg/L vs(2476±324)μg/L](P<005). IL10 of the experimental group was significantly higher than that of the control group[(2153±521)μg/L vs(1769±402)μg/L](P<005).Conclusion Qianlie Shutong Capsules combined with finasteride is effective for benign prostatic hyperplasia, which can effectively improve the clinical symptoms, no obvious complications, has certain safety, and can also adjust the level of inflammatory factors.