【Abstract】Objective To investigatethe psychological status and its influencing factors in patients with pulmonary nodules receiving bronchoscopy, and provide evidence for clinical nursing. Methods Patients with pulmonary nodules receiving bronchoscopy in Department of Respiratory Medicine, West China Hospital, Sichuan University between October 2014 to October 2016 were investigated. Selfrating anxiety scale (SAS) and selfrating depression scale (SDS) were used to evaluate symptoms of anxiety and depression. Results 118 patients completed SDS and SAS. The incidence of anxiety was 449% (52/118), and the incidence of depression was 678% (80/118). Univariate analyses indicated that anxiety was associated with sex, comorbidity, family tumor history, smoking, and education level. The depression was associated with age and marriage status. Multivariate analyses suggested that female, with comorbidity and higher education level were associated with higher incidence of anxiety, and only aged patients were associated with higher incidence of depression. Conclusion The incidence of anxiety and depression in patients with pulmonary nodules receiving bronchoscopy is high. The nurses should take care of these patients according to different situations to improve patients’ quality of life.