【Abstract】Objective To evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) on the postoperative quality of recovery after breast cancer surgery undergoing general anesthesia. Methods 68 patients with American Society of Anesthesiologists physical status (ASA) I or II undergoing breast cancer surgery were randomly allocated to TEAS group and control group. The TEAS group received bilateral Hegu (LI4), Neiguan (PC6) and Zusanli (ST36) TEAS for 30 min before anesthesia induction, whereas the control group received no TEAS. The primary outcome was the quality of recovery, which was assessed at 24h after surgery using the Quality of Recovery 40 questionnaire(QOR40). Secondary outcomes included intraoperative remifentanil consumption, the incidence of postoperative nausea and vomiting(PONV) and patient’s satisfaction. Results Global QOR40 score at 24 h after surgery of TEAS group was higher than that in the control group. Compared with the control group, the cumulative doses of remifentanil was low in the TEAS group patients. Preoperative TEAS reduced the incidence of PONV and improved the patient’s satisfaction scores. Conclusion Preoperative TEAS can enhance the quality of recovery and patient’s satisfaction after general anesthesia for breast cancer surgery.