【Abstract】 Objective To observe the effect of inhaled corticosteroids on patients with cough variant asthma AHR, BPT negative rate and LCQ score. Method 48 cough variant asthma patients were randomly divided into budesonide group, montelukast group and salbutamol group. Three groups of patients were given oxygen, light diet, Bromhexine Hydrochloride Tablets 8mg Po TID and other symptomatic treatment。 On this basis, budesonide group received budesonide 100 g bid inhalation, montelukast group was treated with montelukast sodium 10mg Po QN 100 g salbutamol group received salbutamol inhalation of bid. The course of treatment was 8 weeks. The rate of turn BPT, hyaluronidase (AHR) and LCQ score were observed.Results BPT negative rate of budesonide group was higher than that of montelukast group and salbutamol group (P<005). AHR of the three groups improved after treatment. The effect on AHR of budesonide group demonstrated more advantages than that of montelukast group (P<005). LCQ score of montelukast group and salbutamol group score reduced significantly after treatment (P<001).Conclusion Inhaled corticosteroids can decrease AHR and increase of BPT negative rate and reduce LCQ score.