介入栓塞术与显微外科治疗在前循环动脉瘤破裂出血并发急性脑积水的疗效评价
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四川省医学重点建设学科基金资助项目(川卫办发[2007]407号)


The comparison of interventional and microsurgical treatment of acute hydrocephalus after rupture of anterior circulation aneurysm
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    【摘要】 目的 评价介入治疗与显微外科手术治疗在前循环动脉瘤破裂出血并发急性脑积水的临床特点及疗效. 方法 回顾分析我院近5年来,前循环动脉瘤破裂出血并发急性脑积水患者共89例,按治疗方式分成介入栓塞组(38例)和显微手术组(51例),比较两组术前、术后各临床指标的差异。结果 术前两组情况差异无统计学意义(P>0.05)。术后介入栓塞组较显微手术组有较高的颅内出血的发生率,和较高的动脉瘤残留、复发率(P<0.05)。显微手术组较介入栓塞术有较高的肺部感染率和较低的慢性脑积水发生率(P<0.05)。两组患者的最终死亡率病例,差异无统计学意义(P>0.05),6月后两组GOS评分也差异无统计学意义(P>0.05)。结论 介入栓塞术和显微外科治疗在颅内动脉瘤破裂出血并发急性脑积水的使用中各有优缺点。合理选择治疗方法,趋利避害,将能取得较为理想的效果。

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    【Abstract】 Objective To evaluate the therapeutic effects of interventional and microsurgical treatment of acute hydrocephalus after rupture of anterior circulation aneurysm.Methods 89 patients of acute hydrocephalus after rupture of anterior circulation aneurysm were retrospectively analyzed. The patients were divided into interventional group (38 cases) and microsurgical group (58 cases). The interventional group received intervention of aneurysms and the drainage of cerebrospinal fluid. The microsurgical group received the clipping of aneurysms and the drainage of cerebrospinal fluid. The preoperative and postoperative clinical characters of the two groups were analyzed and compared. Results The preoperative clinical characters of the two groups had no significant differences(P>005). After operation, the interventional group had more intracranial hemorrhages, higher residual or recurrent rates of aneurysm, less pulmonary infection,and more chronic hydrocephalus than that of microsurgical group(P<005). The mortality and GOS of 6 months after operation between the two groups were not significantly different(P>005).Conclusion Intervention and mirosurgery are both facultative therapeutic methods for acute hydrocephalus after rupture of anterior circulation aneurysm. They have advantages and defects. The reasonable therapeutic method according clinical characters of patients can improve the therapy of acute hydrocephalus after rupture of anterior circulation aneurysm.

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  • 在线发布日期: 2017-06-20
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